A Three-Component Reaction Forming Naphthyridones – Synthesis of Lophocladine Analogs
نویسندگان
چکیده
A three-component reaction forming dihydro 2,7-naphthyridine-1-ones has been developed. These unstable dihydro intermediates can be either oxidized or reduced to form naphthyridones or tetrahydro naphthyridones, respectively. The reaction tolerates a large variety of aldehydes and amines, and the produced compounds are analogs of the natural product lophocladine A.
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عنوان ژورنال:
دوره 13 شماره
صفحات -
تاریخ انتشار 2011